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Updated: Jun 27, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Malignant melanoma arising in a burn scar
Emily Ma1, Shealinna Ge2, Walter L Rush3
1University of Maryland School of Medicine, Baltimore Maryland, USA.
Abstract:
Secondary malignancies are rare but devastating complications of longstanding burn scars. Squamous cell carcinoma is the most common, followed by basal cell carcinoma and melanomas. There are fewer than 50 total reported cases of malignant melanomas arising in burn scars. We report a case of malignant melanoma arising within a longstanding burn scar confirmed by histology, FISH, and PRAME staining to further characterize melanomas arising in burn scars and to illustrate the diagnostic challenges they present.
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