Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Extraction: Advanced Methods00:56

Extraction: Advanced Methods

446
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
446
Variability: Analysis01:11

Variability: Analysis

140
Measures of variability are statistical metrics that reveal the dispersion pattern within a dataset. They are pivotal in biostatistics, providing insights into the heterogeneity within health and biological data. Variability signifies the degree to which data points diverge from one another, helping researchers understand the potential range of values and associated uncertainty within the data.
The range is a simple measure of variability, indicating the difference between the highest and...
140
Aggregates Classification01:29

Aggregates Classification

317
Aggregate classification is generally based on its size, petrographic characteristics, weight, and source. Size classification ranges from coarse to fine aggregates, defined by the size of the particles. Coarse aggregates are particles that do not pass through ASTM sieve No. 4, and aggregates that pass through the sieve are fine aggregates.
Petrographic classification groups aggregates based on common mineralogical characteristics. Some of the common mineral groups found in aggregates are...
317
Factorial Design02:01

Factorial Design

13.0K
Factorial Analysis is an experimental design that applies Analysis of Variance (ANOVA) statistical procedures to examine a change in a dependent variable due to more than one independent variable, also known as factors. Changes in worker productivity can be reasoned, for example, to be influenced by salary and other conditions, such as skill level. One way to test this hypothesis is by categorizing salary into three levels (low, moderate, and high) and skills sets into two levels (entry level...
13.0K
Multi-input and Multi-variable systems01:22

Multi-input and Multi-variable systems

106
Cruise control systems in cars are designed as multi-input systems to maintain a driver's desired speed while compensating for external disturbances such as changes in terrain. The block diagram for a cruise control system typically includes two main inputs: the desired speed set by the driver and any external disturbances, such as the incline of the road. By adjusting the engine throttle, the system maintains the vehicle's speed as close to the desired value as possible.
In the absence...
106
Extraction: Partition and Distribution Coefficients01:14

Extraction: Partition and Distribution Coefficients

2.4K
The distribution law or Nernst's distribution law is the law that governs the distribution of a solute between two immiscible solvents. This law, also known as the partition law, states that if a solute is added to the mixture of two immiscible solvents at a constant temperature, the solute is distributed between the two solvents in such a way that the ratio of solute concentrations in the solvents remains constant at equilibrium.
For extracting a solute from an aqueous phase into an...
2.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Left Atrioventricular Coupling Index in Health and Disease: A Longitudinal Multicohort Analysis.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance·2026
Same author

Neutrosophic Extension of the New Odd Weibull-Inverse Weibull Distribution: Theory and Applications.

F1000Research·2026
Same author

Anatomically guided latent diffusion for high-resolution 3D chest CT synthesis.

Scientific reports·2026
Same author

Explainability Challenges in Medical AI: The Conceptual Hidden Cost of Machine Learning Preprocessing.

Health science reports·2026
Same author

Physically Informed 3D Food Reconstruction: Methods and Results.

IEEE journal of biomedical and health informatics·2026
Same author

VolE: A point-cloud framework for food 3D reconstruction and volume estimation.

Scientific reports·2026

Related Experiment Video

Updated: Jun 27, 2025

Quantification of Orofacial Phenotypes in Xenopus
09:26

Quantification of Orofacial Phenotypes in Xenopus

Published on: November 6, 2014

9.7K

Characterizing the Contribution of Dependent Features in XAI Methods.

Ahmed M Salih, Ilaria Boscolo Galazzo, Zahra Raisi-Estabragh

    IEEE Journal of Biomedical and Health Informatics
    |May 2, 2024
    PubMed
    Summary

    This study introduces a new method to improve Explainable Artificial Intelligence (XAI) by accounting for feature dependency, leading to more robust feature rankings in complex models.

    More Related Videos

    Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
    07:35

    Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

    Published on: October 11, 2018

    7.5K
    Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
    09:47

    Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

    Published on: December 15, 2023

    1.0K

    Related Experiment Videos

    Last Updated: Jun 27, 2025

    Quantification of Orofacial Phenotypes in Xenopus
    09:26

    Quantification of Orofacial Phenotypes in Xenopus

    Published on: November 6, 2014

    9.7K
    Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
    07:35

    Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

    Published on: October 11, 2018

    7.5K
    Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
    09:47

    Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

    Published on: December 15, 2023

    1.0K

    Area of Science:

    • Artificial Intelligence
    • Machine Learning Interpretability
    • Medical Data Analysis

    Background:

    • Explainable Artificial Intelligence (XAI) methods enhance model transparency but struggle with multicollinearity.
    • Existing XAI techniques often assume feature independence, which is not always valid.
    • Multicollinearity can compromise the reliability of feature importance rankings in XAI.

    Purpose of the Study:

    • To propose a novel proxy to address multicollinearity in XAI feature ranking.
    • To enhance the robustness and interpretability of XAI outcomes.
    • To provide a method that accounts for feature dependencies.

    Main Methods:

    • A simple proxy was developed to modify existing XAI feature ranking outcomes.
    • The proxy was applied to the SHAP (SHapley Additive exPlanations) method.
    • Cardiac magnetic resonance imaging data was used for a male vs. female classification task with nine cardiac phenotypes as features.
    • Principal Component Analysis and biological plausibility were used for validation.

    Main Results:

    • The proposed proxy effectively accounts for feature dependency in XAI.
    • The modified feature rankings were more robust in the presence of multicollinearity compared to original SHAP.
    • The method successfully revealed the impact of dependent features on model outcomes.

    Conclusions:

    • The developed proxy offers a valuable improvement for XAI methods dealing with multicollinearity.
    • This approach leads to more reliable identification of informative features.
    • The findings contribute to more trustworthy and transparent AI in complex datasets.