Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

178
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
178
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

140
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
140
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

241
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
241
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

324
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
324
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

3.3K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.3K
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

226
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
226

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thermally air oxidation of activated carbon for enhanced lead(II) removal with preliminary insights into CO<sub>2</sub> and <sup>222</sup>radon adsorption.

Environmental science and pollution research international·2026
Same author

Electrochemical biosensors: a novel approach for rapid and cost-effective hCG monitoring in gestational trophoblastic tumours.

RSC advances·2026
Same author

High-sensitivity electrochemical immunosensor for anti-SARS-CoV-2 IgG detection using screen-printed carbon/cerium oxide-gold electrode.

ADMET & DMPK·2026
Same author

Graphene-supported Pd/Pt nano-catalysts for enhanced colorimetric detection of dopamine and NADH using paper-based microfluidic devices.

ADMET & DMPK·2026
Same author

Advances in biosensor technologies for early diagnosis of preeclampsia through molecular biomarkers.

Methods (San Diego, Calif.)·2026
Same author

The Effect of Variations in Temperature and Contact Time of Zingerone, [6]-Gingerol and Shogaol as Disinfectants on <i>Staphylococcus aureus</i>, <i>Escherichia coli</i>, <i>Pseudomonas aeruginosa</i> and <i>Candida albicans</i>.

Microorganisms·2026

Related Experiment Video

Updated: Jun 27, 2025

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.1K

Multidrug-resistant tuberculosis.

Dika Apriliana Wulandari1, Yeni Wahyuni Hartati1, Abdullahi Umar Ibrahim2

  • 1Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang Km 21, 45363, Indonesia.

Clinica Chimica Acta; International Journal of Clinical Chemistry
|May 2, 2024
PubMed
Summary

Tuberculosis (TB) is a major global health threat. Rapid molecular detection of multidrug-resistant TB (MDR-TB) is crucial to combat its spread and reduce mortality.

Keywords:
Detection method of MDR-TBMultidrug-resistant tuberculosisTB biomarkersTuberculosis

More Related Videos

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
07:35

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

Published on: April 25, 2014

12.7K
System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
09:57

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis

Published on: April 5, 2017

8.6K

Related Experiment Videos

Last Updated: Jun 27, 2025

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.1K
Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
07:35

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

Published on: April 25, 2014

12.7K
System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
09:57

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis

Published on: April 5, 2017

8.6K

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Genetics

Background:

  • Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a leading cause of global mortality.
  • Inadequate treatment can foster drug resistance, with multidrug-resistant TB (MDR-TB) being a significant concern.
  • MDR-TB arises from mutations in rpoB and katG genes, conferring resistance to rifampicin (RIF) and isoniazid (INH).

Purpose of the Study:

  • To review biomarkers for MDR-TB detection.
  • To discuss anti-TB drugs and resistance-conferring mutations.
  • To highlight the need for rapid MDR-TB diagnostics to reduce global morbidity and mortality.

Main Methods:

  • Literature review on MDR-TB diagnostics.
  • Classification of biomarkers for MTB detection.
  • Analysis of genetic mutations linked to drug resistance.

Main Results:

  • Traditional culturing methods for TB diagnosis are slow.
  • Molecular techniques offer sensitive and specific alternatives for detecting MDR-TB.
  • Specific gene mutations (rpoB, katG) are associated with resistance to key anti-TB drugs.

Conclusions:

  • Rapid and accurate detection of MDR-TB is essential for effective treatment and control.
  • Molecular diagnostics are vital for timely intervention against MDR-TB.
  • Reducing MDR-TB incidence requires enhanced diagnostic strategies and awareness.