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Clinical Effectiveness of Transversus Abdominis Plane (TAP) Block versus Local Anesthesia Wound Infiltration for

Geoffrey Bloy1, Amelie Jurine1, Yann Chaussy2

  • 1CHU Besançon, Département d'Anesthésie Réanimation Chirurgicale, Besançon, F-25000, France.

Journal of Pain Research
|May 3, 2024
PubMed

Insights

This study compares transversus abdominis plane (TAP) blocks to local anesthesia (LA) wound infiltration for pediatric appendectomy pain. It hypothesizes TAP blocks offer better opioid-sparing effects, aiding early recovery after surgery.

Area of Science:

  • Pediatric surgery
  • Anesthesiology
  • Pain management

Background:

  • Effective postoperative pain management is crucial for children's recovery after laparoscopic appendectomy.
  • Current guidelines suggest transversus abdominis plane (TAP) blocks or local anesthesia (LA) wound infiltration for analgesia.
  • No direct comparison exists between TAP blocks and LA wound infiltration in pediatric appendectomy patients.

Purpose of the Study:

  • To compare the clinical effectiveness of TAP blocks versus LA wound infiltration for postoperative pain relief in children undergoing laparoscopic appendectomy.
  • To determine if TAP blocks provide a greater opioid-sparing effect than LA wound infiltration.

Main Methods:

  • A multicenter, double-blind, randomized controlled phase III trial involving 110 children.
  • Participants randomized to either TAP block or LA wound infiltration.
  • Standardized multimodal analgesia including paracetamol, phloroglucinol, ketoprofene, and nalbuphine, with pain assessed using the FLACC scale.

Main Results:

  • Primary outcome is the total nalbuphine dose administered within 24 hours post-surgery.
  • Data collection and analysis are ongoing.
  • Results will quantify the opioid-sparing effect of each intervention.

Conclusions:

  • This trial will provide high-level evidence comparing TAP blocks and LA wound infiltration for pediatric appendectomy analgesia.
  • Findings will inform clinical guidelines for postoperative pain management in this population.
Abstract

Keywords:
TAP blockanalgesiachildrenlaparoscopic appendectomywound infiltration

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