Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Imaging01:14

Brain Imaging

228
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
228

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of the Flavor Profiles of Fresh and Hot-Air-Dried Ginger (<i>Zingiber officinale</i> Roscoe) by Molecular Sensory Science.

Foods (Basel, Switzerland)·2026
Same author

Complex Deep Neural Networks for Denoising Ultra-Fast Submillimeter T2*-weighted Imaging and Quantitative Susceptibility Mapping.

European journal of radiology artificial intelligence·2026
Same author

Challenges and future directions for multiple sclerosis after the 2024 McDonald diagnostic criteria.

Nature medicine·2026
Same author

Relationship between cerebrospinal fluid neurobiomarkers and symptoms in older patients with cognitive impairment: an observational clinical study.

Scientific reports·2026
Same author

Effects of Compound Probiotics on Production Performance, Apparent Digestion Rate of Nutrients and Serum Index of Pigs at Different Stages.

Animals : an open access journal from MDPI·2026
Same author

The "Brain's Traffic Map" Reveals Neural Pathways Linked to Coronary Microvascular Dysfunction in Women.

Brain and behavior·2026

Related Experiment Video

Updated: Jun 27, 2025

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

1.1K

The Brain's First "Traffic Map" through Unified Structural and Functional Connectivity (USFC) Modeling.

Arzu Has Silemek1, Haitao Chen1, Pascal Sati1

  • 1Cedars-Sinai Medical Center.

Research Square
|May 3, 2024
PubMed
Summary

The brain

Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Brain Connectomics

Background:

  • Understanding how the brain's structural white matter pathways support functional communication between distant regions is crucial but poorly understood.
  • Existing models often analyze structural and functional connectivity separately, limiting a holistic view of brain communication efficiency.

Approach:

  • Developed a Unified Structural and Functional Connectivity (USFC) model incorporating an "economical assumption" to simulate brain traffic flow.
  • Created the first brain "traffic map" quantifying the usage frequency of individual white matter connection segments.
  • Utilized the USFC model to analyze network efficiency and identify key communication pathways.

Key Points:

  • The USFC traffic map reveals subcortical, default-mode, and salience networks as highly utilized hubs.

More Related Videos

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

26.2K
Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging
11:57

Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging

Published on: February 24, 2021

10.0K

Related Experiment Videos

Last Updated: Jun 27, 2025

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

1.1K
Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

26.2K
Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging
11:57

Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging

Published on: February 24, 2021

10.0K
  • A prominent midline corridor (frontal-caudate-thalamus-posterior cingulate-visual cortex) serves as the brain's primary connectivity backbone.
  • Negative functional connections exhibit an inverse relationship with structural connectivity strength.
  • The USFC connectome demonstrates superior efficiency metrics compared to standalone structural or functional connectomes.

    • Conclusions:

    • The USFC model provides a novel framework for brain connectome modeling and mapping.
    • This approach offers significant advancements in understanding the brain's fundamental communication mechanisms and network efficiency.
    • Highlights the importance of integrating structural and functional data for a comprehensive brain connectivity analysis.