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  11. Genetic Landscape Of Hearing Loss In The Caribbean: A Narrative Review.

Genetic Landscape of Hearing Loss in the Caribbean: A Narrative Review.

LéShon Peart1, Mustafa Tekin1,2

  • 1Dr. John T. Macdonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, FL, USA.

Balkan Medical Journal
|May 3, 2024

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View abstract on PubMed

Summary
This summary is machine-generated.

Hereditary hearing loss (HL) varies across Caribbean populations due to diverse genetics and environmental factors. This review guides future research and healthcare strategies for HL in this diverse region.

Area of Science:

  • Genetics
  • Public Health
  • Audiology

Background:

  • The Caribbean has a diverse population of 40 million across 13 nations.
  • Hereditary hearing loss (HL) is a significant health concern in diverse populations.
  • Understanding HL in the Caribbean is crucial for targeted interventions.

Purpose of the Study:

  • To systematically review existing studies on hereditary hearing loss (HL) in the Caribbean.
  • To describe HL prevalence, genetic causes, technology use, and environmental effects.
  • To inform future research and healthcare strategies for HL in the Caribbean and diaspora.

Main Methods:

  • Systematic literature review of scientific articles.
  • Focused on Caribbean nations and the US Caribbean diaspora.

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  • Analyzed studies on HL prevalence, genetics, technology, and environmental factors.

    • Main Results:

    • HL rates and genetic variables differ across Puerto Rico, Cuba, and the Dominican Republic.
    • Local resources and technology aid HL diagnosis, especially in rural areas.
    • Environmental factors significantly influence HL prevalence in various regions.

    Conclusions:

    • This review highlights the need for region-specific approaches to hereditary hearing loss.
    • Findings guide future research, particularly on genetic drift due to migration.
    • Improved understanding can enhance HL diagnosis and treatment in diverse populations.