Bronchiectasis in Türkiye: Data from a Multicenter Registry (Turkish Adult Bronchiectasis Database)

Area of Science:

• Pulmonology
• Epidemiology
• Clinical Research

Background:

• Bronchiectasis is a chronic lung disease involving permanent bronchial wall dilatation.
• Previously considered an orphan disease, it's gaining research attention.
• Understanding its characteristics in Türkiye is crucial for targeted interventions.

Purpose of the Study:

• To analyze and compare bronchiectasis data in Türkiye with international findings.
• To investigate etiology, comorbidities, microbiology, and prevention strategies.
• To establish a comprehensive profile of bronchiectasis within the Turkish population.

Main Methods:

• A multicenter prospective cohort study involving 25 centers in Türkiye.
• Data collected from 1,035 adult patients diagnosed with non-cystic fibrosis bronchiectasis.
• Included demographic, etiological, comorbidity, microbiological, and clinical data.

Main Results:

• Post-infectious origin (39.5%) and tuberculosis (11.3%) were key etiologies.
• Cardiovascular disease and COPD were common comorbidities (19.5% had both).
• Pseudomonas aeruginosa was the most frequent microbe; inhaled corticosteroids use correlated with higher exacerbations and mortality risk.

Conclusions:

• This is the first multicenter bronchiectasis study in Türkiye.
• Results provide crucial data for developing health policies on infection control and treatment.
• Findings emphasize the need for tailored strategies for bronchiectasis management in Türkiye.