United States marijuana legalization and opioid mortality trends before and during the first year of the COVID-19 pandemic

  • 0Oregon Health and Science University, Portland, Oregon; University of Texas McGovern Medical School, Houston, Texas. ORCID: https://orcid.org/0000-0001-7738-5146.

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Summary

This summary is machine-generated.

Marijuana legalization in the US was linked to increased opioid and fentanyl death rates. Recreational marijuana legalization correlated with greater opioid mortality, especially during the COVID-19 pandemic.

Area Of Science

  • Public Health
  • Epidemiology
  • Substance Abuse Research

Background

  • Investigating the association between marijuana legalization and opioid mortality trends in the United States.
  • Examining the impact of varying marijuana legalization policies on opioid-related deaths.

Purpose Of The Study

  • To determine if marijuana legalization was associated with reduced opioid mortality.
  • To compare opioid mortality trends in states with and without marijuana legalization.

Main Methods

  • Comparative analysis of US opioid mortality data from 2010-2019.
  • Utilized Joinpoint methodology on Centers for Disease Control and Prevention WONDER data.
  • Compared acceleration of opioid mortality in 2020 during the COVID-19 pandemic across recreational and medicinal-only legalizing jurisdictions.

Main Results

  • Jurisdictions legalizing marijuana showed higher increases in opioid and fentanyl death rates (2010-2019).
  • By 2019, all-opioid and fentanyl death rates were 44% and 50% greater, respectively, in legalizing versus non-legalizing jurisdictions.
  • Recreational marijuana legalization was associated with significantly greater increases in opioid and fentanyl mortality during the COVID-19 pandemic in 2020.

Conclusions

  • Marijuana legalization at the jurisdiction level correlated with accelerated opioid death rates over the past decade.
  • Recreational marijuana legalization was linked to a more pronounced increase in opioid mortality with the onset of the COVID-19 pandemic.
  • Findings suggest marijuana legalization is correlated with a worsening of the US opioid epidemic.

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