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Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
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Photofunctional Gold Nanocluster Composites for Bioapplications
Yujie Cong1, Jiaren Liu1, Jingkai Zhang1
1State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.
ACS Applied Bio Materials
|May 3, 2024
Summary
Gold nanoclusters (AuNCs) offer unique optical properties for biomedical applications. This review explores AuNC assembly and composite functions for enhanced biological sensing and optical treatments, highlighting future prospects.
Area of Science:
- Nanotechnology
- Materials Science
- Biomedical Engineering
Background:
- Gold nanoclusters (AuNCs) possess tunable structures and optical properties, making them valuable for biological applications.
- Assembling AuNCs into composite systems enhances their inherent optical performance for diagnostic and therapeutic uses.
- Understanding AuNC assembly behaviors is crucial for optimizing their function in biological fields.
Purpose of the Study:
- To review prevalent interactions and assembly modes in AuNC-based nanocomposites and microcomposites.
- To demonstrate the functions of AuNC composites for various bioapplications, including sensing and optical treatments.
- To discuss the future prospects, challenges, and opportunities of AuNC composites in biomedical applications.
Main Methods:
- Review of existing literature on AuNC assembly and composite formation.
- Analysis of different interaction types and assembly strategies for AuNCs.
- Detailed examination of functional demonstrations of AuNC composites in biological sensing and optical therapies.
Main Results:
- Multiple interactions and assembly modes for AuNCs in composite systems were identified.
- AuNC composites inherit and enhance the optical properties of individual AuNCs.
- These enhanced properties enable diverse requirements for biological sensing and optical treatments.
Conclusions:
- AuNC composites show significant promise for advanced biomedical applications.
- Further research into assembly behaviors and performance enhancement is warranted.
- Addressing challenges in fabrication and clinical translation is key for future opportunities.
