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Related Concept Videos

Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...

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Ultrafast 3-D Transcutaneous Super Resolution Ultrasound Using Row-Column Array Specific Coherence-Based Beamforming

Joseph Hansen-Shearer1, Jipeng Yan1, Marcelo Lerendegui1

  • 1Imperial College London, London, UK.

Ultrasound in Medicine & Biology
|May 3, 2024
PubMed
Summary
This summary is machine-generated.

This study developed new processing methods to improve 3-D super-resolution ultrasound imaging using a row-column array. These techniques enable high-quality, non-invasive microvascular imaging in vivo for both research and clinical applications.

Keywords:
3-D ultrasoundBeamformingCoherenceFrame multiply and sumHigh frame rate/ultrafast imagingImage reconstructionReal-timeRow-column arraySuper-resolution ultrasoundUltrasound localisation microscopy

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Area of Science:

  • Medical Imaging
  • Ultrasound Technology
  • Biomedical Engineering

Background:

  • Traditional 2-D matrix arrays for ultrasound imaging have limitations in channel count and field of view.
  • Row-column arrays offer advantages but typically yield poor in vivo image quality, especially for non-invasive applications.
  • Improving image quality is crucial for advanced ultrasound techniques like ultrasound localisation microscopy.

Purpose of the Study:

  • To develop image formation and post-processing methods for 3-D super-resolution ultrasound imaging using a row-column array.
  • To enhance the image quality of row-column arrays for non-invasive imaging applications.
  • To demonstrate the feasibility of ultrasound localisation microscopy with a row-column array in vivo.

Main Methods:

  • Developed a processing pipeline incorporating rolling window image reconstruction.
  • Integrated a row-column array specific coherence-based beamforming with acoustic sub-aperture processing.
  • Implemented methods to reduce secondary lobe artifacts and noise, and increase effective frame rate.

Main Results:

  • Reduced 'false' locations in vitro from ~26% to ~15% compared to orthogonal plane wave compounding.
  • Achieved a noise reduction of ~7 dB and increased effective frame rate to over 4000 fps.
  • Successfully produced non-invasive ultrasound localisation microscopy images of a rabbit kidney and a human thyroid in vivo.

Conclusions:

  • Demonstrated that proposed methods enable large field of view super-resolution microvascular imaging with a row-column array.
  • Confirmed the feasibility of non-invasive in vivo super-resolution ultrasound imaging in both animal models and humans.
  • The developed techniques significantly improve the utility of row-column arrays for advanced medical imaging.