Related Experiment Video
Updated: Jun 27, 2025

Conducting Respiratory Oscillometry in an Outpatient Setting
Published on: April 8, 2022
Objective monitoring tools for improved management of childhood asthma
Phillip L W Au-Doung1, Jason C H Chan1, Oliver Y H Kui1
1School of Pharmacy, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong SAR, China.
Insights
Objective tools can improve childhood asthma monitoring, aiding early detection and effective treatment. This review explores spirometry, FeNO, and EMDs for better pediatric asthma management.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
- Clinical Research
Background:
- Childhood asthma remains a significant global health concern with high mortality rates.
- Effective asthma control is crucial to prevent potentially fatal exacerbations.
- Current subjective monitoring methods lack reliability due to reliance on self-perception.
Purpose of the Study:
- To review the prevalence and severity of childhood asthma globally.
- To evaluate the effectiveness of emerging objective monitoring tools in pediatric asthma.
- To provide insights for standardizing objective monitoring in clinical practice.
Main Methods:
- Systematic review of publications from 2016-2023 on objective pediatric asthma monitoring tools.
- Included studies on spirometry, fractional exhaled nitric oxide (FeNO), hyperresponsiveness tests, and electronic monitoring devices (EMDs).
- Analysis focused on the efficacy, advantages, and limitations of each tool.
Main Results:
- Objective tools like spirometry, FeNO, and EMDs show promise for more accurate asthma assessment.
- These tools can aid in detecting disease progression and treatment response.
- A lack of consensus currently hinders the standardization of these objective methods.
Conclusions:
- Objective monitoring tools offer significant potential to enhance the management of childhood asthma.
- Further research is needed to establish standardized protocols for their clinical use.
- Clinicians can benefit from understanding the capabilities of various objective tools for improved patient care.
Abstract:
Asthma is a common chronic disease amongst children. Epidemiological studies showed that the mortality rate of asthma in children is still high worldwide. Asthma control is therefore essential to minimize asthma exacerbations, which can be fatal if the condition is poorly controlled. Frequent monitoring could help to detect asthma progression and ensure treatment effectiveness. Although subjective asthma monitoring tools are available, the results vary as they rely on patients' self-perception. Emerging evidence suggests several objective tools could have the potential for monitoring purposes. However, there is no consensus to standardise the use of objective monitoring tools. In this review, we start with the prevalence and severity of childhood asthma worldwide. Then, we detail the latest available objective monitoring tools, focusing on their effectiveness in paediatric asthma management. Publications of spirometry, fractional exhaled nitric oxide (FeNO), hyperresponsiveness tests and electronic monitoring devices (EMDs) between 2016 and 2023 were included. The potential advantages and limitations of each tool were also discussed. Overall, this review provides a summary for researchers dedicated to further improving objective paediatric asthma monitoring and provides insights for clinicians to incorporate different objective monitoring tools in clinical practices.
Related Concept Videos
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-IV: Nursing Management
First, in...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Inhaled Medications
COPD: Management Using Bronchodilators and Corticosteroids
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...

