Pipelle Endometrial Sampling With a Full Bladder Compared With Standard Care: A Randomized Controlled Trial

Area of Science:

• Gynecology
• Minimally Invasive Procedures

Background:

• Endometrial sampling is crucial for diagnosing gynecologic conditions.
• Pipelle endometrial sampling is a common outpatient procedure.
• Insertion failures and patient discomfort can complicate endometrial sampling.

Purpose of the Study:

• To compare the insertion failure rates of Pipelle endometrial sampling using a full bladder versus the standard process.
• To evaluate the impact of a full bladder on pain, satisfaction, and procedure duration.

Main Methods:

• A single-masked randomized trial involving 214 participants was conducted.
• Participants were randomized to either a full bladder group or a standard process group.
• Exclusion criteria included cervical stenosis, uterine anomalies, and previous failed sampling.

Main Results:

• The insertion failure rate was significantly lower in the full bladder group (23.4%) compared to the standard process group (42.1%).
• The full bladder group reported significantly less pain (P=.004) and higher patient satisfaction (P<.001).
• Procedure duration was also significantly shorter in the full bladder group (P<.001).

Conclusions:

• Performing Pipelle endometrial sampling with a full bladder is an effective strategy to reduce insertion failure rates.
• This technique improves patient experience by decreasing pain and procedure time.
• A full bladder approach enhances patient satisfaction during endometrial sampling.