Related Experiment Video

Updated: Jun 20, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

11.7K

Comparison between transcatheter versus surgical intervention for pediatric aortic valvular stenosis: a multicenter

Jun Muneuchi1, Ayako Kuraoka2, Yusaku Nagatomo3

  • 1Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, 1-8-1, Kishinoura, Yahatanishi-Ku, Kitakyushu, Fukuoka, 806-8501, Japan. jmune@msn.com.

Heart and Vessels
|May 4, 2024
PubMed

Insights

For pediatric aortic valvular stenosis, both balloon aortic valvuloplasty (BAV) and surgical aortic valvuloplasty (SAV) show similar long-term survival and reintervention rates. This study compared outcomes for children undergoing either BAV or SAV for vAS.

Area of Science:

  • Pediatric Cardiology
  • Interventional Cardiology
  • Congenital Heart Disease

Background:

  • Aortic valvular stenosis (vAS) in children presents a treatment dilemma regarding initial intervention.
  • Transcatheter balloon aortic valvuloplasty (BAV) and surgical aortic valvuloplasty (SAV) are primary treatment options.
  • Outcomes comparing BAV and SAV in pediatric vAS require further investigation.

Purpose of the Study:

  • To compare the long-term outcomes of transcatheter balloon aortic valvuloplasty (BAV) versus surgical aortic valvuloplasty (SAV) in pediatric patients with isolated aortic valvular stenosis (vAS).
  • To analyze differences in survival rates, need for reintervention, and rates of valve replacement between BAV and SAV groups.
  • To identify factors influencing freedom from reintervention and valve replacement.

Main Methods:

  • A multicenter retrospective case-control study involving 73 children (<15 years) with vAS from 4 tertiary congenital heart centers.
  • Comparison of 10-year survival, reintervention, and prosthetic/autograft valve replacement rates between BAV and SAV cohorts.
  • Propensity score-matched analysis was performed to control for confounding variables.

Main Results:

  • No significant differences were observed in 10-year survival (BAV: 88% vs. SAV: 92%), reintervention rates (BAV: 58% vs. SAV: 31%), or valve replacement (BAV: 21% vs. SAV: 19%) between BAV and SAV groups.
  • Freedom from reintervention correlated with aortic annulus z-score (HR 0.66, P=0.005).
  • Freedom from valve replacement correlated with post-intervention aortic regurgitation (HR 4.58, P=0.027).
  • Propensity score-matched analysis (N=16) confirmed no significant differences in survival or reintervention rates.

Conclusions:

  • Both BAV and SAV offer acceptable long-term survival for pediatric vAS.
  • Rates of freedom from reintervention and valve replacement are comparable between BAV and SAV.
  • Aortic annulus size and degree of aortic regurgitation are significant factors influencing long-term outcomes.

Keywords:
Balloon dilatationCongenital heart diseaseOutcomes: Aortic stenosisValve replacementValvotomy

More Related Videos

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model05:31

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

2.8K
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

1.6K

Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...