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Updated: May 11, 2026

Intravitreous Injection for Establishing Ocular Diseases Model
Published on: October 1, 2007
[Injection of cefuroxime into the vitreous cavity leading to toxic retinal damage: a case report]
1Xiamen Eye Center of Xiamen University, Fujian Provincial Key Laboratory of Ocular Surface & Corneal Diseases, Xiamen Municipal Key Laboratory of Ocular Surface & Corneal Diseases, Xiamen Municipal Key Laboratory of Ocular Diseases, Xiamen Clinical Research Center for Eye Diseases, Xiamen 361002, China.
Abstract:
A 36-year-old male patient presented with a decrease in vision after undergoing scleral suturing for a left eye injury caused by an iron hook, combined with intravitreal injection of cefuroxime. Ocular examination revealed extensive gray-white edematous areas in the macular region, along with focal serous shallow retinal detachment in the posterior pole. Following admission, comprehensive ophthalmic examinations were conducted, leading to the diagnosis of toxic retinal damage in the left eye. Treatment with oral corticosteroids and interventions to improve microcirculation were initiated, resulting in improved visual acuity. At the six-month follow-up, the patient's visual acuity had recovered to 0.5.
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