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Updated: Jun 27, 2025

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Transtubular Endoscopic Posterolateral Decompression for L5-S1 Lumbar Lateral Disc Herniation
Published on: October 14, 2022
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S1 Radiculopathy Initially Presenting With Sole Knee Flexion Weakness: A Case Report
Stavros Stamiris1, Christos Karampalis1, Dimitris Stamiris1
1Department of Orthopaedics, 424 General Military Hospital, Thessaloniki, GRC.
Cureus
|May 6, 2024
Summary
A rare case of S1 radiculopathy presented initially with hamstring weakness and posterior knee pain, delaying diagnosis. This atypical presentation of lumbar disc herniation highlights the need for broader diagnostic considerations.
Area of Science:
- Neurology
- Orthopedics
- Neurosurgery
Background:
- Lumbar disc herniation commonly causes low back pain and sciatica.
- S1 radiculopathy, resulting from L5-S1 disc herniation, typically presents with foot weakness and altered sensation.
Observation:
- A case of S1 radiculopathy initially manifested solely with hamstring weakness and posterior knee pain.
- This atypical presentation led to a diagnostic delay.
Findings:
- The study reports an unusual S1 radiculopathy presentation not previously documented.
- Hamstring weakness and posterior knee pain can be initial signs of S1 radiculopathy.
Implications:
- Clinicians should consider S1 radiculopathy in patients with atypical posterior knee pain and hamstring weakness.
- Broadening the differential diagnosis can prevent diagnostic delays and improve patient outcomes.
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