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Updated: Jun 27, 2025

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Published on: August 21, 2013
Knowledge, Attitudes, and Perceptions of Skin Cancer Clinical Trials in the Hispanic Population
Luis F Andrade1, Maria J Lalama2, Siri Choragudi2
1Dermatology, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, USA.
Insights
Hispanic patients show positive attitudes towards skin cancer clinical trials, indicating potential motivational factors for increased participation. Understanding these beliefs can help bridge the gap in trial enrollment for this demographic.
Area of Science:
- Dermatology
- Clinical Trials
- Health Disparities
Background:
- Hispanic populations are underrepresented in dermatological clinical trials, comprising only 1% of enrolled patients despite making up 18.5% of the US population.
- Identifying barriers and motivators for Hispanic patient participation is crucial for improving clinical trial diversity.
Purpose of the Study:
- To investigate factors influencing the participation of Hispanic patients in dermatological clinical trials.
- To identify potential motivational drivers for this demographic.
Main Methods:
- A 31-item in-person questionnaire was administered to patients at a large free clinic serving a predominantly Hispanic population and a private primary care clinic.
- Data collection occurred between January 2022 and July 2022.
Main Results:
- Hispanic patients expressed significantly greater agreement with statements regarding attitudes and behavioral beliefs compared to non-Hispanic respondents.
- Key motivators included the belief that "My community would really benefit from skin cancer clinical trials," "My participation in a skin cancer study would be very good," and a general desire "I like to do good for others."
Conclusions:
- Positive attitudes and altruistic beliefs among Hispanic patients suggest avenues for increasing their involvement in skin cancer clinical trials.
- Addressing these motivational factors could help reduce the disparity in clinical trial enrollment for Hispanic individuals.
Objective:
To determine the factors that might limit Hispanic patients from participating in dermatological clinical trials.
Methods:
From January 2022 to July 2022, we administered a 31-item, in-person questionnaire to patients recruited in the waiting area of the Caridad Center, one of the largest free clinics in the United States with a predominately Hispanic population, and a nearby private primary care clinic.
Results:
Overall, Hispanic patients agreed significantly more with statements in the domain of attitude and behavioral beliefs compared to non-Hispanic survey respondents. The Hispanic ethnicity was associated with increased odds of agreeing with the following statements: "My community would really benefit from skin cancer clinical trials" (OR=0.52; 95% CI 0.30, 0.92), "My participation in a skin cancer study would be very good" (OR=0.59; 95% CI 0.35, 0.99), and "I like to do good for others" (OR=0.41; 95% CI 0.22, 0.77).
Conclusion:
While the United States population is composed of 18.5% Hispanics, they only account for 1% of patients enrolled in clinical trials. This study helps identify potential motivational factors for Hispanic patients to participate in skin cancer clinical trials.
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