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Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

320
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
320
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

228
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
228
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

117
Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
117
Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

376
Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
376
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

794
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
794
Flame Photometry: Lab01:16

Flame Photometry: Lab

243
In a flame photometer, when a solution like potassium chloride is aspirated into the flame, the solvent evaporates, leaving behind dehydrated salt. This salt dissociates into free gaseous atoms in their ground state. Some of these atoms absorb energy from the flame, leading to their excitation. The excited atoms return to the ground state, emitting photons at characteristic wavelengths. Because only electronic transitions are involved, the resulting emission lines are very narrow. The intensity...
243

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Related Experiment Video

Updated: Jun 27, 2025

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response
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Phytophotodermatitis From Lime Margaritas on a Mexico Vacation.

Brigitte L Cochran1, Jennifer Jallo2, Alexis Coican3

  • 1Osteopathic Medicine, Philadelphia College of Osteopathic Medicine, Moultrie, USA.

Cureus
|May 6, 2024
PubMed
Summary

Phytophotodermatitis, a skin reaction from plant chemicals and sun exposure, can present unusually. A case highlights how lime contact and sun caused a back patch, emphasizing thorough history and examination.

Keywords:
furocoumarinphotodermatitisphytophotodermatitisplant biochemistrysun exposure

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Area of Science:

  • Dermatology
  • Toxicology
  • Photobiology

Background:

  • Phytophotodermatitis is a skin reaction caused by furocoumarins from plants and subsequent sun exposure.
  • It is a form of contact dermatitis with varied clinical presentations.
  • Citrus plants are common sources of photosensitizing furocoumarins.

Observation:

  • A 34-year-old patient presented with an asymptomatic, hyperpigmented patch on their back after a beach vacation.
  • The lesion's appearance was irregular and atypical.
  • The patient recalled consuming a lime margarita and rubbing their hand on their back.

Findings:

  • The clinical presentation and history were consistent with phytophotodermatitis.
  • The reaction was attributed to furocoumarins from lime contacting the skin, followed by sun exposure.
  • The patient's back patch was a result of autoinoculation from hand to back.

Implications:

  • Accurate diagnosis of phytophotodermatitis requires a detailed patient history, including recent sun exposure and potential contact with phytotoxic plants.
  • Awareness of varied presentations is crucial to avoid misdiagnosis and unnecessary treatments like topical corticosteroids.
  • This case underscores the importance of a comprehensive physical examination and patient history in diagnosing cutaneous reactions.