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Modifiable Physical Factors That Influence Physical Function for People Receiving Peritoneal Dialysis
Brett Tarca1, Shilpanjali Jesudason2,3, Paul N Bennett4,5
1Alliance for Research in Exercise, Nutrition and Activity, Allied Health and Human Performance, University of South Australia, Adelaide, Australia.
Kidney International Reports
|May 6, 2024
Summary
Cardiorespiratory fitness is key to maintaining physical function in peritoneal dialysis patients. Monitoring and improving fitness can prevent decline and enhance quality of life.
Area of Science:
- Nephrology
- Exercise Physiology
- Gerontology
Background:
- Peritoneal dialysis (PD) patients often experience physical function decline, impacting daily activities and quality of life.
- Physical factors like cardiorespiratory fitness, muscle strength, and physical activity are linked to physical function, but their temporal changes in PD patients are understudied.
Purpose of the Study:
- To explore modifiable physical factors associated with physical function in PD patients.
- To identify the factor with the strongest influence on physical function.
- To investigate temporal changes in these factors over 12 months.
Main Methods:
- Adult PD patients (n=82) underwent assessments of physical function, cardiorespiratory fitness, muscle strength, physical activity, and sedentary behavior.
- Assessments were conducted at baseline, 6 months, and 12 months.
Main Results:
- Cardiorespiratory fitness demonstrated the strongest association with both self-reported and objective physical function.
- Significant temporal declines were observed in cardiorespiratory fitness (-9.8%), quadricep strength (-5%), and physical activity levels.
- Sedentary behavior increased by 7.1% over the 12-month period.
Conclusions:
- Cardiorespiratory fitness is a critical, modifiable factor for maintaining physical function in PD patients and warrants routine monitoring.
- Interventions targeting cardiorespiratory fitness can enhance physical function and quality of life.
- A multifactorial approach considering all physical factors is essential for interventions aimed at mitigating decline and promoting physical activity benefits.
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