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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Summary

Postinflammatory hyperpigmentation (PIH) after Mohs surgery is more common in individuals with skin of color (SOC), especially those with Fitzpatrick skin types IV-V. Factors like grafts, granulation, and complications increase PIH risk.

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Area of Science:

Dermatology
Surgical Oncology
Cosmetic Science

Background:

Functional and cosmetic outcomes of Mohs micrographic surgery (MMS) in skin of color (SOC) are understudied.
Postinflammatory hyperpigmentation (PIH) can be a significant and distressing outcome for SOC patients following dermatologic procedures.

Purpose of the Study:

To identify and characterize factors contributing to the development of PIH after Mohs micrographic surgery in individuals with skin of color.

Main Methods:

Retrospective study of 72 SOC individuals undergoing Mohs micrographic surgery for keratinocyte carcinoma.
Data collected from August 2020 to August 2021 at a single medical center.

Main Results:

PIH was more frequent in Fitzpatrick skin types IV-V (48.0%) compared to I-III (18.2%).
Grafts and granulation led to higher PIH rates (87.5%) than linear repairs/flaps (30.7%).
Postoperative complications (81.8%) and specific sutures (polyglactin 910, 46.2%) also increased PIH risk.

Conclusions:

Individuals with SOC, particularly Fitzpatrick skin types IV-V, face a higher risk of PIH post-MMS.
Surgical techniques (grafts, granulation) and postoperative complications are significant risk factors for PIH.
Surgeons should consider these factors to mitigate PIH in SOC patients undergoing Mohs surgery.