Classification of 2-node excitatory-inhibitory networks
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Updated: Jun 27, 2025

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
Published on: June 24, 2015
Manuela Aguiar1, Ana Dias2, Ian Stewart3
1Centro de Matemática da Universidade do Porto (CMUP), Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre s/n, 4169-007, Porto, Portugal; Faculdade de Economia, Universidade do Porto, Rua Dr Roberto Frias, 4200-464 Porto, Portugal.
Abstract:
We classify connected 2-node excitatory-inhibitory networks under various conditions. We assume that, as well as for connections, there are two distinct node-types, excitatory and inhibitory. In our classification we consider four different types of excitatory-inhibitory networks: restricted, partially restricted, unrestricted and completely unrestricted. For each type we give two different classifications. Using results on ODE-equivalence and minimality, we classify the ODE-classes and present a minimal representative for each ODE-class. We also classify all the networks with valence ≤2. These classifications are up to renumbering of nodes and the interchange of 'excitatory' and 'inhibitory' on nodes and arrows. These classifications constitute a first step towards analysing dynamics and bifurcations of excitatory-inhibitory networks. The results have potential applications to biological network models, especially neuronal networks, gene regulatory networks, and synthetic gene networks.
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