Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sidelobe suppressed Bessel beams for one-photon light-sheet microscopy.

Biomedical optics express·2024
Same author

Multimodal mechano-microscopy reveals mechanical phenotypes of breast cancer spheroids in three dimensions.

APL bioengineering·2024
Same author

UVA Hyperspectral Light-Sheet Microscopy for Volumetric Metabolic Imaging: Application to Preimplantation Embryo Development.

ACS photonics·2023
Same author

Spatially offset optical coherence tomography: Leveraging multiple scattering for high-contrast imaging at depth in turbid media.

Science advances·2023
Same author

Experimentally unsupervised deconvolution for light-sheet microscopy with propagation-invariant beams.

Light, science & applications·2022
Same author

Does artificial intelligence have a role in the IVF clinic?

Reproduction & fertility·2022

Related Experiment Video

Updated: Jun 27, 2025

Bioinspired Soft Robot with Incorporated Microelectrodes
08:24

Bioinspired Soft Robot with Incorporated Microelectrodes

Published on: February 28, 2020

8.8K

Light-deformable microrobots shape up for the biological obstacle course.

Philip Wijesinghe1

  • 1Centre of Biophotonics, SUPA, School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews, Fife, KY16 9SS, UK. pw64@st-andrews.ac.uk.

Light, Science & Applications
|May 6, 2024
PubMed
Summary

Researchers engineered the Euglena gracilis microalga into a soft bio-microrobot. This innovative microrobot exhibits light-controlled movement and shape-shifting for applications in drug delivery and cell therapy.

More Related Videos

Design and Fabrication of an Elastomeric Unit for Soft Modular Robots in Minimally Invasive Surgery
11:06

Design and Fabrication of an Elastomeric Unit for Soft Modular Robots in Minimally Invasive Surgery

Published on: November 14, 2015

8.9K
Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1
11:22

Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1

Published on: July 11, 2017

8.1K

Related Experiment Videos

Last Updated: Jun 27, 2025

Bioinspired Soft Robot with Incorporated Microelectrodes
08:24

Bioinspired Soft Robot with Incorporated Microelectrodes

Published on: February 28, 2020

8.8K
Design and Fabrication of an Elastomeric Unit for Soft Modular Robots in Minimally Invasive Surgery
11:06

Design and Fabrication of an Elastomeric Unit for Soft Modular Robots in Minimally Invasive Surgery

Published on: November 14, 2015

8.9K
Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1
11:22

Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1

Published on: July 11, 2017

8.1K

Area of Science:

  • Biotechnology
  • Microfluidics
  • Bio-robotics

Background:

  • Microalgae like Euglena gracilis are versatile biological platforms.
  • Developing controllable micro-scale robots is crucial for advanced biomedical applications.

Purpose of the Study:

  • To engineer Euglena gracilis into a functional bio-microrobot.
  • To demonstrate light-controlled motion and deformation for targeted bio-challenges.

Main Methods:

  • Genetic transformation of Euglena gracilis.
  • Utilizing light stimuli to control micro-robot behavior.
  • In vitro testing for biomedical applications.

Main Results:

  • Successfully transformed Euglena gracilis into a light-responsive bio-microrobot.
  • Demonstrated precise control over motion and deformation using light.
  • Validated potential for drug delivery, cell removal, and photodynamic therapy.

Conclusions:

  • Euglena gracilis can be engineered into sophisticated bio-microrobots.
  • Light-controlled micro-robots offer a promising platform for minimally invasive biomedical interventions.