Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Acid-base changes and ventilator mode during maintenance ventilation.

R G Hooper, M Browning

    Critical Care Medicine
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Prehabilitation of Patients With Oesophageal Malignancy Undergoing Peri-Operative Treatment (Pre-EMPT): Outcomes From a Prospective Controlled Trial.

    Journal of surgical oncology·2025
    Same author

    Modeling Hydrogen Markets: Energy System Model Development Status and Decarbonization Scenario Results.

    Energy and climate change·2025
    Same author

    The promise of layer-specific neuroimaging for testing predictive coding theories of psychosis.

    Schizophrenia research·2020
    Same author

    Effect of broiler genetics, age, and gender on performance and blood chemistry.

    Heliyon·2020
    Same author

    Why women are not small men: sex-related differences in perioperative cardiopulmonary exercise testing.

    Perioperative medicine (London, England)·2020
    Same author

    Pathogenicity of Xanthomonas translucens from Annual Bluegrass on Golf Course Putting Greens.

    Plant disease·2019
    Same journal

    The authors reply.

    Critical care medicine·2026
    Same journal

    Attracting Emergency Medicine Graduates to Surgical Critical Care Training Programs.

    Critical care medicine·2026
    Same journal

    The authors reply.

    Critical care medicine·2026
    Same journal

    Beyond a Snapshot: Tracking Family Prognostic Expectations in the ICU.

    Critical care medicine·2026
    Same journal

    The authors reply.

    Critical care medicine·2026
    Same journal

    Plasma Levels of Soluble ST2 Reflect Extrapulmonary Organ Dysfunction and Predict Outcomes in Acute Respiratory Failure: Beware of Potential Confounders.

    Critical care medicine·2026
    See all related articles

    Assist-control ventilation led to more respiratory-induced alkalemia than intermittent mandatory ventilation (IMV) in post-surgery patients. IMV resulted in fewer acid-base changes, suggesting it may be a safer ventilation mode.

    Area of Science:

    • Cardiology
    • Pulmonary Medicine
    • Critical Care Medicine

    Background:

    • Coronary bypass surgery patients often require mechanical ventilation.
    • Choosing the appropriate ventilation mode is crucial for patient recovery and preventing complications.

    Purpose of the Study:

    • To compare the effects of assist-control ventilation and intermittent mandatory ventilation (IMV) on acid-base balance in post-coronary bypass surgery patients.
    • To evaluate ventilator-induced acid-base changes between the two ventilation modes.

    Main Methods:

    • A comparative study involving 35 patients without prior respiratory disease undergoing coronary bypass surgery.
    • Patients received respiratory support via either assist-control ventilation or high-rate IMV.
    • Spontaneous respiratory rates, minute ventilation, and arterial blood gases (PaCO2, pH) were measured.

    Related Experiment Videos

    Main Results:

    • No significant differences in spontaneous respiratory rates or minute ventilation were observed between groups.
    • Assist-control ventilation was associated with significantly lower PaCO2 and higher pH compared to IMV.
    • Six cases of severe respiratory alkalemia occurred during assist-control ventilation, linked to higher settings and extra delivered volumes.

    Conclusions:

    • Intermittent mandatory ventilation (IMV) was associated with fewer ventilator-induced acid-base disturbances compared to assist-control ventilation.
    • Assist-control ventilation may increase the risk of respiratory alkalemia in this patient population.
    • IMV may be a preferable mode for minimizing acid-base complications in post-coronary bypass surgery patients.