Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 27, 2025

Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics

Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics

Published on: December 8, 2011

A Multiresolution Approach with Method-Informed Statistical Analysis for Quantifying Lymphatic Pumping Dynamics.

Mohammad S Razavi, Katarina J Ruscic, Elizabeth G Korn

Biorxiv : the Preprint Server for Biology

|May 7, 2024

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Rediscovering the Ciucci pathway: in-vivo evidence of a palmar lymphatic channel.

Breast cancer research and treatment·2026

Same author

Immortalized smooth muscle cells enhance in vitro vasculogenesis.

Research square·2026

Same author

Immortalized smooth muscle cells enhance in vitro vasculogenesis.

bioRxiv : the preprint server for biology·2026

Same author

A hybrid multiscale model for predicting CAR-T therapy outcomes in solid tumors.

Scientific reports·2026

Same author

Superficial and Functional Imaging of the Posterior Upper Arm Pathway in the Healthy Population.

Journal of surgical oncology·2026

Same author

Synaptic dysfunction and traumatic brain injury.

Neural regeneration research·2026

Same journal

Layered social competition coordinates reproductive hierarchy formation in ants.

bioRxiv : the preprint server for biology·2026

Same journal

Combination epigenetic-targeted therapy increases the immunogenicity of poorly immunogenic sarcomas.

bioRxiv : the preprint server for biology·2026

Same journal

Loss of LanC-like proteins delays post-injury regeneration of aging skeletal muscles.

bioRxiv : the preprint server for biology·2026

Same journal

Integrative Transfer Network: Deep Transfer Learning Across Populations and Prediction Targets.

bioRxiv : the preprint server for biology·2026

Same journal

Confidence-supported label-free metabolic imaging with FPhaS phase autofluorescence microscopy.

bioRxiv : the preprint server for biology·2026

Same journal

Sequence-encoded autoinhibition couples mRNA decapping activity to phase separation.

bioRxiv : the preprint server for biology·2026

See all related articles

This study introduces a new quantitative method for analyzing lymphatic contractility using near-infrared lymphangiography. The approach enhances diagnostic reliability for lymphatic disorders by integrating advanced signal processing and statistical analysis.

Area of Science:

Biomedical Engineering
Physiology
Medical Imaging

Background:

Accurate diagnosis of lymphatic disorders is hindered by a lack of standardized, quantitative methods for real-time lymphatic contractility analysis.
Current imaging techniques often lack the precision needed for reliable functional assessment of the lymphatic system.

Purpose of the Study:

To develop and validate an innovative analytical workflow for quantitative, real-time assessment of lymphatic contractility.
To improve the reliability and diagnostic utility of near-infrared lymphangiography for lymphatic function evaluation.

Main Methods:

Integration of near-infrared lymphangiography with advanced signal processing, including wavelet time-frequency analysis.
Application of decision theory to optimize measurement reliability by identifying key drivers of variance.

More Related Videos

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema

Published on: January 12, 2017

Related Experiment Videos

Last Updated: Jun 27, 2025

Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics

Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics

Published on: December 8, 2011

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema

Published on: January 12, 2017

Inclusion of multiple regions of interest and varied gravitational loads during data acquisition.

Main Results:

The developed workflow provides detailed insights into lymphatic pumping behaviors across different species, sexes, and ages.
Measurement reliability was significantly enhanced through comprehensive data acquisition and analysis strategies.
The approach demonstrated the ability to capture the dynamic behavior of the lymphatic system more effectively.

Conclusions:

This study establishes a new standard for imaging and analyzing lymphatic function, crucial for understanding and diagnosing lymphatic diseases.
The findings underscore the importance of robust data acquisition and quantitative analysis for advancing lymphatic research and clinical applications.
The developed method has the potential to improve the diagnosis and treatment of various lymphatic disorders.