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Updated: Jun 27, 2025

Surgery and Sample Processing for Correlative Imaging of the Murine Pulmonary Valve
Published on: August 5, 2021
A modifiable valve-sparing pediatric cardiac dissection technique promotes specimen longevity and optimizes advanced
Takato Yamasaki1,2, Shuhei Toba1,2, Stephen P Sanders1,3
1The Cardiac Registry, Departments of Cardiology, Pathology, and Cardiac Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.
Abstract:
This paper illustrates a valve-sparing cardiac dissection technique that keeps the atrioventricular and semilunar valves and other important cardiac structures intact. The technique minimizes disruption in heart specimens, so they remain suitable for teaching, demonstration, and further research. When performed following the perfusion-distension method of fixation, as our group previously described, this technique could optimize the preservation of heart specimens for teaching and digital archiving postdissection.

