Blood microsampling technologies: Innovations and applications in 2022.

Area of Science:

• Biomedical analysis
• Analytical chemistry
• Clinical diagnostics

Background:

• Advancements in bioanalytical techniques have decreased required sample volumes.
• Microsampling offers minimal invasiveness, reduced costs, and enhanced sample stability.
• Despite benefits, clinical adoption of microsampling remains slow.

Purpose of the Study:

• To review the state-of-the-art in microsampling technology.
• To assess recent advancements and applications in microsampling.
• To evaluate the advantages, challenges, and limitations of current microsampling methods.

Main Methods:

• Review of research published in 2022 focusing on microsampling.
• Analysis of studies on analyte quantitation in microsamples.
• Examination of studies comparing microsampling matrices and technologies.

Main Results:

• Microsampling technologies are increasingly used in research.
• Studies in 2022 focused on quantitation strategies and matrix/technology comparisons.
• Challenges remain in standardization and harmonization for clinical practice.

Conclusions:

• Microsampling facilitates patient-centric, data-rich healthcare.
• Standardization is crucial for routine clinical implementation.
• Microsampling is poised to be central to digital healthcare and continuous monitoring.