Related Experiment Video
Updated: Jun 26, 2025
10:27
Preparation of Highly Porous Coordination Polymer Coatings on Macroporous Polymer Monoliths for Enhanced Enrichment of Phosphopeptides
Published on: July 14, 2015
10.1K
Recent developments and applications of polymer monolithic stationary phases
Sebastiaan Eeltink1, Daniel Meston1, Frantisek Svec2
1Department of Chemical Engineering Vrije Universiteit Brussel (VUB) Brussels Belgium.
Analytical Science Advances
|May 8, 2024
Summary
This review covers recent advances in organic polymer monoliths for separations, focusing on preparation, anchoring, and structural tuning for enhanced performance. Key applications and method development using these novel monolithic columns are also discussed.
Area of Science:
- Materials Science
- Analytical Chemistry
- Chromatography
Background:
- Organic polymer-based monolithic materials are crucial in separation science.
- Previous research established foundational techniques for their preparation and application.
Purpose of the Study:
- To review recent trends and advances in organic polymer monoliths published in 2020.
- To discuss protocols for covalent anchoring of monoliths.
- To explore structure-property relationships and applications.
Main Methods:
- Literature review of publications from 2020.
- Discussion of covalent anchoring strategies.
- Analysis of macroporous structure tuning and its impact on separation performance.
Main Results:
- Significant advances in the preparation and functionalization of organic polymer monoliths.
- Improved understanding of how macroporous structure influences separation efficiency.
- Development of novel monolithic columns with enhanced performance.
Conclusions:
- Organic polymer monoliths continue to evolve with new preparation and application strategies.
- Tuning the macroporous structure is key to optimizing separation performance.
- Novel monolithic columns show promise for various analytical applications.
Related Concept Videos
01:17Gas Chromatography: Types of Columns and Stationary Phases
612
Gas chromatography (GC) relies on stationary phases to separate and analyze components in a sample. There are two main types of stationary phases: liquid and solid. Liquid stationary phases are non-volatile, thermally stable, and chemically inert liquids coated onto the column. Solid stationary phases are particles of adsorbent material, such as silica gel or molecular sieves.
For an analyte to remain on the column for a sufficient amount of time, it must exhibit some level of compatibility (or...
For an analyte to remain on the column for a sufficient amount of time, it must exhibit some level of compatibility (or...
612
01:11High-Performance Liquid Chromatography: Introduction
2.0K
High-performance liquid chromatography(HPLC), formerly referred to as High-pressure liquid chromatography, is a powerful technique used to separate, identify, and quantify components in complex mixtures. The term "high pressure" refers to using high pressure to push the liquid mobile phase through the tightly packed columns.
In HPLC, two phases play a critical role in the separation process:
In HPLC, two phases play a critical role in the separation process:
2.0K
01:10Silica Gel Column Chromatography: Overview
1.2K
Silica gel column chromatography is a technique for separating compounds using a column packed with silica gel as the stationary phase. This method relies on differences in the polarity of compounds. Based on their polarities, compounds move between the stationary phase (silica gel) and the mobile phase (the solvent), forming discrete bands in the column.
Polar components tend to bind strongly to the silica gel, causing them to move slowly through the column. In contrast, nonpolar compounds...
Polar components tend to bind strongly to the silica gel, causing them to move slowly through the column. In contrast, nonpolar compounds...
1.2K
01:09Analyte Adsorption and Distribution
643
In certain chromatographic separations, solutes transfer between the mobile phase and the stationary phase via sorption, which typically refers to the process of adsorption. For many chromatographic systems, the sorption process often depends on the polarity of the compounds—an expression of the overall dipole moment within the molecule. During the separation process, there is competition between the solute and solvent for adsorption to the stationary phase. Highly polar compounds and...
643
01:17Ziegler–Natta Chain-Growth Polymerization: Overview
3.3K
Ziegler–Natta polymerization is another form of addition or chain‐growth polymerization used for synthesizing linear polymers over branched polymers. The catalyst used for polymerization is the Ziegler–Natta catalyst, named after Karl Ziegler and Giulio Natta, who developed it in 1953. This catalyst is an organometallic complex of titanium tetrachloride and triethyl aluminum, with the active form of the catalyst being an alkyl titanium compound. Using the Ziegler–Natta...
3.3K
01:09Ion-Exchange Chromatography
450
Ion-exchange chromatography, or IEC, is a technique for separating ions based on their affinity for the stationary phase. The stationary phase is a cross-linked polymer resin with covalently attached ionic functional groups. The functional groups can be either positively charged (cation exchangers) or negatively charged (anion exchangers). A cation exchanger consists of a polymeric anion and active cations, while an anion exchanger is a polymeric cation with active anions. The choice of...
450