Multiple facial hemangiomas and iron-deficiency anemia: blue rubber-bleb nevus syndrome

A 21-year-old female complained of bluish soft tumors on her face. Her past history of anemia led us to investigate a possibility of "Blue Rubber-Bleb Nevus syndrome." Subsequent examinations revealed a severe iron-deficiency anemia and gastrointestinal tract hemangiomas. The facial hemangiomas were removed after controlling anemia. It is important to examine the gastrointestinal tract when multiple cutaneous hemangiomas are associated with anemia.