Preexisting Diabetes and Breast Cancer Treatment Among Low-Income Women
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View abstract on PubMed
Summary
This summary is machine-generated.Women with diabetes were less likely to receive and complete breast cancer adjuvant therapies, including radiotherapy, chemotherapy, and endocrine therapy. This highlights the need for better diabetes management during cancer treatment for low-income populations.
Area Of Science
- Oncology
- Endocrinology
- Public Health
Background
- Diabetes is linked to worse breast cancer outcomes.
- The impact of diabetes on breast cancer adjuvant therapies is not well understood.
Purpose Of The Study
- To investigate the association between preexisting diabetes and the use of radiotherapy, chemotherapy, and endocrine therapy in low-income women with breast cancer.
Main Methods
- A population-based cohort study of low-income women diagnosed with nonmetastatic breast cancer (2007-2015).
- Logistic regression analysis was used to compare adjuvant therapy utilization, initiation, completion, adherence, and persistence between women with and without diabetes.
- Analyses were adjusted for sociodemographic and tumor characteristics.
Main Results
- Women with diabetes were less likely to utilize radiotherapy (OR, 0.67), receive chemotherapy (OR, 0.67), complete chemotherapy (OR, 0.71), and adhere to endocrine therapy (OR, 0.71) compared to women without diabetes.
- No significant associations were found for endocrine therapy utilization/persistence or timely initiation/completion of radiotherapy and chemotherapy.
Conclusions
- Preexisting diabetes is associated with reduced receipt and adherence to adjuvant therapies for breast cancer in low-income women.
- Improved diabetes management is crucial for this vulnerable population to mitigate disparities in cancer treatment and outcomes.
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