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Open source approaches for pediatric global health technologies.

Ryan C L Brewster1,2, Andrew Wu3, Ryan W Carroll4

  • 1Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.

Journal of Medical Engineering & Technology
|May 8, 2024
PubMed
Summary

Open-source approaches can accelerate the development of medical technologies for children, especially in low-resource settings. This democratised innovation model balances collaboration with essential safety and quality standards for pediatric global health.

Keywords:
Global healthmedical devicesmedical technologyopen sourcepaediatrics

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Area of Science:

  • Biomedical innovation
  • Global health technology
  • Pediatric medical devices

Background:

  • Advancement of medical technologies for children lags behind adults due to market size, variability, and regulatory challenges.
  • Low-resource settings (LRS) face magnified barriers in pediatric innovation, including inadequate regulatory oversight and supply chain capacity.
  • The COVID-19 pandemic highlighted limitations in traditional medical technology models and spurred interest in open-source solutions.

Purpose of the Study:

  • To explore the potential of open-source approaches to accelerate the development and dissemination of pediatric medical technologies.
  • To address the unique barriers in developing and commercializing innovations for children, particularly in low-resource settings.
  • To advocate for open-source pathways as a means to foster equitable and sustainable medical innovations for children globally.

Main Methods:

  • The study presents a conceptual argument for open-source pathways in pediatric global health.
  • It analyzes how open-source models can overcome economic barriers and leverage low-cost manufacturing.
  • It discusses the importance of stakeholder engagement and regulatory considerations for open-source medical technologies.

Main Results:

  • Open-source approaches can be tailored to clinical needs, are adaptable, and facilitate customization.
  • These pathways empower diverse stakeholders, including patients and families, in collaborative innovation.
  • Open-source models can address critical equipment shortages and promote equitable access.

Conclusions:

  • Open-source strategies offer significant potential to advance equitable and sustainable medical innovations for children worldwide.
  • Balancing democratized innovation with safety and quality is crucial for pediatric solutions.
  • Coordination between regulatory agencies and decentralized networks can ensure the safety and efficacy of open-source pediatric technologies.