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Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering
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Concerns about data integrity across 263 papers by one author.

Jeremy Nielsen1, Madeline Flanagan1, Lyle C Gurrin2

  • 1Department of Obstetrics and Gynecology, Monash University, Clayton, Australia.

Journal of Gynecology Obstetrics and Human Reproduction
|May 8, 2024
PubMed
Summary

An investigation into an author with eight retractions found data integrity issues in 49% of their papers. Over a third of these papers showed concerns suggesting unreliable data collection from human participants.

Keywords:
Data integrityRandomised clinical trialResearch integrityScientific misconduct

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Area of Science:

  • Medical research integrity
  • Academic publishing ethics
  • Clinical trial data analysis

Background:

  • Comprehensive investigation of published work by authors suspected of academic misconduct can reveal further concerns.
  • An author with eight retracted articles was identified for further scrutiny.

Purpose of the Study:

  • To test for data integrity concerns in papers published by an author with a history of retractions.
  • To assess the reliability of data reported in clinical studies authored by this individual.

Main Methods:

  • Investigated all papers reporting on prospective clinical studies by the author.
  • Assessed study methods, baseline characteristics, outcomes, and publication consistency.
  • Recalculated p-values and identified duplicate publications.

Main Results:

  • 263 papers were identified, claiming 74,667 participants (2009-2022).
  • Data integrity concerns were found in 130 (49%) papers.
  • Concerns suggesting unreliable data were present in 43 (33%) of the papers with integrity issues.

Conclusions:

  • Widespread integrity concerns were found in the author's collected work.
  • A formal investigation by involved journals is recommended.
  • Ensuring data reliability in clinical research is paramount.