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Isolation of Leukocytes from the Human Maternal-fetal Interface
Published on: May 21, 2015
Increased plasma interleukin-1 activity in women after ovulation
Science (New York, N.Y.)
|March 8, 1985
Abstract:
The polypeptide interleukin-1 mediates many host responses to infection and inflammation. A method was developed for studying interleukin-1 levels in human plasma from febrile patients. Interleukin-1 activity was also consistently found in plasma samples from women in the luteal phase of their menstrual cycle. This activity was neutralized by a specific antiserum to human interleukin-1 and was low in plasma from healthy men and preovulatory women. Thus interleukin-1 appears to have a role in normal physiological conditions as well as in disease states.
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