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Updated: Jun 26, 2025
08:37
Assessment of Glutamine as a Fuel Source for Alveolar Macrophages Exposed to Chronic Ethanol Using an Extracellular Flux Bioanalyzer
Published on: November 15, 2024
318
The association between alcohol consumption and pulmonary function: a scoping review.
Line Bjerrehave Nielsen1,2, Maria Oxbøl Johansen3, Signe Juul Riddersholm2,4
1Department of Respiratory Diseases, Aalborg University Hospital, Aalborg, Denmark L.bjerrehave@rn.dk.
Summary
Heavy alcohol consumption harms pulmonary function, while moderate intake may offer benefits. The relationship between alcohol and lung health requires further investigation due to study limitations.
Area of Science:
- Pulmonary Medicine
- Public Health
- Toxicology
Background:
- The health impacts of alcohol are known, but its effect on pulmonary function is debated.
- Existing research suggests a U-shaped association: moderate alcohol intake may be beneficial, while heavy consumption is detrimental.
Purpose of the Study:
- To investigate the association between alcohol consumption and pulmonary function.
- To explore potential protective effects of moderate alcohol intake and harmful effects of heavy drinking on lung function.
Main Methods:
- A comprehensive literature search was conducted across multiple databases (PubMed, Embase, Cochrane, CINAHL).
- Studies were evaluated using the Joanna Briggs Institute (JBI) methodological framework for scoping reviews.
- Data extraction and qualitative analysis were performed by two independent reviewers.
Main Results:
- Out of 30 eligible studies, 10 reported negative effects of alcohol on pulmonary function, nine found no impact, and nine indicated a positive effect.
- Two studies suggested a nonlinear, U-shaped association between alcohol intake and pulmonary function parameters.
Conclusions:
- The U-shaped curve hypothesis for alcohol and pulmonary function is not definitively confirmed by current literature.
- Heavy alcohol consumption appears detrimental to lung function, whereas low to moderate intake may have a positive influence.
- Study quality variations, inconsistent alcohol quantification, and smoking confounders necessitate further high-quality, long-term international research.
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