Related Experiment Video
Updated: Jun 26, 2025

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
Resuscitation for injured patients requiring massive transfusion: A personal perspective
1From the Department of Surgery, Detroit Receiving Hospital, Detroit Medical Center, Wayne State University School of Medicine, Detroit, Michigan.
Abstract:
The past century has seen many advances in the field of resuscitation. This is particularly true in the subset of patients who sustain major injuries causing hemorrhagic shock (HS) and require massive transfusion of more than 10 U of blood within the first 24 hours. Controversies on how best to resuscitate these patients include the role of fresh whole blood, stored whole blood, fresh frozen plasma, platelets, colloid solutions, balanced electrolytes solution, vasopressors, and diuretics. This review summarizes the often-contradictory recommendations observed and studied by a single trauma surgeon working in a busy urban acute care center for 65 years.
Level Of Evidence:
Level I.
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