Outcome and Factors Related to Isolated Liver Metastasis due to Breast Cancer
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Long-term survival is achievable for breast cancer patients with liver metastasis. Developing metastasis more than three years after initial treatment is linked to better progression-free survival.
Area Of Science
- Oncology
- Surgical Oncology
- Medical Statistics
Background
- Breast cancer is a leading cause of cancer-related mortality worldwide.
- Liver metastasis significantly impacts patient prognosis and treatment strategies.
- Hepatic surgery offers a potential treatment modality for select patients with liver metastases.
Purpose Of The Study
- To identify risk factors associated with isolated liver metastasis in breast cancer patients.
- To determine prognostic factors influencing survival in these patients.
- To evaluate the outcomes of surgical intervention for breast cancer liver metastasis.
Main Methods
- Retrospective analysis of 12 breast cancer patients who underwent surgery for liver metastasis.
- Descriptive statistics for patient and metastasis characteristics.
- Kaplan-Meier method for survival analysis, with Log-rank and Cox regression tests for prognostic factor identification.
Main Results
- Out of 12 patients, 11 had recurrent disease, and one had de novo metastasis.
- Grade 3 tumors and high Ki-67 expression negatively impacted disease-free survival (DFS).
- Development of liver metastasis within 3 years of treatment correlated with worse progression-free survival (PFS) (p=0.040).
Conclusions
- Long-term survival is feasible for breast cancer patients with liver metastasis.
- The disease-free interval is a critical determinant of prognosis.
- Patients developing metastasis after three years demonstrated longer PFS.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
