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Updated: Jul 6, 2026

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
07:21

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking

Published on: February 12, 2011

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Incremental Prognostic Value of Left Atrial Strain in Patients With Suspected Myocarditis and Preserved Left

Yan Chen1, Nan Zhang1, Wenjing Zhao1

  • 1Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Journal of Magnetic Resonance Imaging : JMRI
|May 9, 2024
PubMed

Insights

Left atrial conduit strain predicts major adverse cardiovascular events in patients with suspected myocarditis and preserved ejection fraction. Left atrioventricular coupling index did not show prognostic value.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Biomarkers

Background:

  • Left atrial (LA) strain and left atrioventricular coupling index (LACI) are recognized prognostic markers in cardiovascular diseases.
  • Their prognostic utility in patients with suspected myocarditis and preserved left ventricular ejection fraction (LVEF) remains underexplored.

Purpose of the Study:

  • To evaluate the prognostic significance of LA strain and LACI in patients with suspected myocarditis and preserved LVEF.
  • To compare these markers against established MRI-based predictors of cardiovascular outcomes.

Main Methods:

  • Retrospective analysis of 165 patients with suspected myocarditis and preserved LVEF.
  • Cardiovascular magnetic resonance (CMR) imaging using 3.0T MRI, including cine and late gadolinium enhancement sequences.
  • Feature tracking for LA and left ventricular (LV) strain analysis; LACI calculated from LA and LV volumes.

Main Results:

  • Left ventricular strain parameters and LACI were not significantly associated with major adverse cardiovascular events (MACE).
  • Left atrial conduit strain (Ԑe) showed a significant association with MACE in both univariable and multivariable Cox analyses (HR 0.936, P=0.041).
  • An optimal LA conduit strain cutoff of 10.4% effectively stratified patients into low- and high-risk groups for MACE.

Conclusions:

  • Left atrial conduit strain serves as a valuable prognostic indicator in patients diagnosed with suspected myocarditis and preserved LVEF.
  • LA conduit strain provides incremental prognostic information beyond conventional MRI predictors.
  • LACI was not found to be associated with MACE in this patient cohort.
Abstract

Keywords:
feature trackingleft atrial strainmyocarditis

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