Related Experiment Video
Updated: Oct 1, 2026

An Orthotopic Resectional Mouse Model of Pancreatic Cancer
Published on: September 24, 2020
Alpha 1-antitrypsin and cancer of the pancreas
Abstract:
Serum levels of alpha-1-antitrypsin (alpha 1-AT) were measured and phenotypes were determined in 47 patients with cancer of the pancreas and in 160 hospital controls. The mean value of alpha 1-AT (+/- SEM) in cases with cancer of the pancreas was 486 (+/- 18) mg/100 ml, and it was significantly higher than the corresponding mean value in controls, which was 434 (+/- 13) mg/100 ml (p approximately 0.02). The frequency distribution of the cases of pancreatic cancer by alpha 1-AT phenotype was: M1M1 49%, M1M3 21% and other phenotypes 30%, whereas the corresponding frequency distribution among controls was: M1M1 53%, M1M3 21% and other phenotypes 26%; the two distributions are clearly compatible (p greater than 0.50).
Related Concept Videos
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Acute Pancreatitis I: Introduction
Acute Pancreatitis II: Pathophysiology
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis II: Pathophysiology

