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Does sorghum phenolic extract have antifungal effect?

Renata Regina Pereira da Conceição1, Valéria Aparecida Vieira Queiroz2, Maria Lúcia Ferreira Simeone3

  • 1Department of Microbiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais (UFMG), Avenida Antônio Carlos, no 6.627, Belo Horizonte, MG, 31270-901, Brazil.

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The SC319 sorghum phenolic extract (SPE) showed no antifungal effects against common plant pathogens. However, SPE may promote beneficial fungi growth, delaying fungal development in early incubation stages.

Keywords:
Sorghum bicolor (L.) MoenchBiofungicideMinimum inhibitory concentrationToxigenic fungi

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Area of Science:

  • Agricultural Science
  • Mycology
  • Biochemistry

Background:

  • Fungal diseases pose significant threats to crop yields and food security.
  • Sorghum phenolic extracts (SPE) are explored for potential bioactivities.
  • Understanding plant extracts' effects on fungi is crucial for developing sustainable agricultural practices.

Purpose of the Study:

  • To evaluate the antifungal efficacy of SC319 sorghum phenolic extract (SPE) against key fungal genera.
  • To determine the Minimum Inhibitory Concentration (MIC) and Conidial Germination Rate (CGR) of SPE.
  • To investigate the impact of SPE on fungal growth dynamics.

Main Methods:

  • SPE was extracted using 20% ethanol.
  • Assays included direct fungal growth inhibition, MIC, CGR, and Growth Curve (GC) analysis.
  • Tested against Aspergillus, Fusarium, Penicillium, Stenocarpella, Colletotrichum, and Macrophomina species.

Main Results:

  • SPE did not inhibit mycelial growth or spore count of Fusarium verticillioides.
  • MIC values for SPE exceeded 5000 µg/mL against 16 fungal isolates.
  • SPE showed no inhibitory effect on conidia germination rate (CGR).
  • SPE demonstrated a potential to delay fungal growth in the initial 24 hours of incubation.

Conclusions:

  • SC319 SPE lacks significant antifungal activity against the tested fungal genera.
  • SPE may possess plant growth-promoting properties for beneficial fungi.
  • Further research is needed on diverse sorghum genotypes and their phenolic compounds.