Ameloblastic Carcinoma With Orbital Invasion.

Area of Science:

• Oncology
• Oral and Maxillofacial Surgery
• Ophthalmology

Background:

• Ameloblastic carcinoma is a rare malignant odontogenic tumor characterized by ameloblastic differentiation and cytological malignancy.
• Orbital invasion by ameloblastic carcinoma is uncommon, typically affecting orbital structures like the floor, apex, or soft tissues.

Observation:

• A 58-year-old male presented with a large mid-facial mass causing intracranial invasion and affecting cranial foramina, nasopharynx, nasal cavity, and both orbits.
• The tumor exhibited an en-plaque pattern along orbital walls, compressing the orbital apex and causing proptosis without breaching the extraconal space.
• Histological examination confirmed nests of ameloblastic carcinoma.

Findings:

• This case represents an advanced, nonresectable ameloblastic carcinoma with extensive orbital and intracranial involvement.
• The tumor demonstrated a unique en-plaque growth pattern within the orbits.

Implications:

• This presentation underscores the aggressive potential of ameloblastic carcinoma and the challenges in managing advanced orbital invasion.
• Palliative treatment strategies are crucial for nonresectable cases of ameloblastic carcinoma with extensive invasion.
• Further research into the behavior and management of orbital ameloblastic carcinoma is warranted.