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Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores

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Published on: August 19, 2013

Iron modified hydrogen-bonded organic framework as fluorescent sensor for ascorbic acid detection.

Shangqing Zhang¹, Jie Wen¹, Haiyan Li¹

¹Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang, 110819, China.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy

|May 9, 2024

Summary

This summary is machine-generated.

A novel iron-modified hydrogen-bonded organic framework (Fe-HOF) enables sensitive detection of ascorbic acid (AA). This fluorescent sensor offers rapid quantification of AA in various products.

Keywords:

2, 5-dihydroxyterephthalic acid Ascorbic acid Fe-HOF HOF

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Area of Science:

Materials Science
Analytical Chemistry
Nanotechnology

Background:

Hydrogen-bonded organic frameworks (HOFs) are emerging porous materials with tunable properties.
Metal ion modification can enhance the functionality of HOFs for sensing applications.
Ascorbic acid (AA) is a vital nutrient with important biological and industrial relevance, necessitating accurate detection methods.

Purpose of the Study:

To develop a sensitive and rapid fluorescence-based sensor for ascorbic acid (AA) detection.
To utilize an iron-modified hydrogen-bonded organic framework (Fe-HOF) as the sensing platform.
To investigate the responsive mechanism of Fe-HOF to AA for quantitative analysis.

Main Methods:

Synthesis of Fe-HOF by incorporating 2,5-dihydroxyterephthalic acid and Fe3+ into a HOF structure.
Development of a 'turn-on' fluorescence strategy based on the redox reaction between Fe3+ and AA.
Characterization of the Fe-HOF material and evaluation of its sensing performance for AA.

Main Results:

Successful preparation of yellow-green fluorescent Fe-HOF.
Fe3+ in Fe-HOF effectively quenched fluorescence; AA reduced Fe3+ to Fe2+, restoring fluorescence.
Linear fluorescence response for AA detection in the range of 0.5–8 μM with a limit of detection (LOD) of 0.14 μM.
Demonstrated rapid and accurate detection of AA in vitamin C pills, tablets, and beverages with good recoveries.

Conclusions:

The developed Fe-HOF based 'turn-on' fluorescence strategy provides a sensitive and selective method for AA detection.
This sensing platform offers a rapid, reliable, and practical approach for analyzing AA in real-world samples.
Fe-HOF materials hold promise for developing advanced fluorescent sensors in analytical chemistry.