Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sensory processing in a thermal afferent pathway.

S N Davies, G E Goldsmith, R F Hellon

    Journal of Neurophysiology
    |February 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The attribution of human health outcomes to climate change: a transdisciplinary guidance document.

    Climatic change·2025
    Same author

    Systematic Implementation of Effective Quality Assurance Processes for the Assessment of Radiation Target Volumes in Head and Neck Cancer.

    Practical radiation oncology·2024
    Same author

    Stability of retinol in liposomes as measured by fluorescence lifetime spectroscopy and FLIM.

    BBA advances·2023
    Same author

    Psychopathology and eating behaviour in people with type 2 diabetes referred for bariatric surgery.

    Eating and weight disorders : EWD·2022
    Same author

    Exploring utilisation of the allied health assistant workforce in the Victorian health, aged care and disability sectors.

    BMC health services research·2021
    Same author

    Eight new <i>Elaphomyces</i> species (<i>Elaphomycetaceae, Eurotiales, Ascomycota</i>) from eastern North America.

    Fungal systematics and evolution·2021
    Same journal

    Deep Learning Reveals Cross-Modal Neural Representations of Auditory and Visual Mental Imagery in MEG.

    Journal of neurophysiology·2026
    Same journal

    Speech sensorimotor adaptation in young adult cochlear implant users with early implantation.

    Journal of neurophysiology·2026
    Same journal

    How Visual Context Influences Lateral Stepping Regulation While Walking on Winding Paths.

    Journal of neurophysiology·2026
    Same journal

    Simultaneous neuron evidence for much higher covariation with saccadic reaction time of superior colliculus than primary visual cortex visual responses.

    Journal of neurophysiology·2026
    Same journal

    Separate Dorsolateral Prefrontal Cortex Regions Participate in Distinct Large-Scale Networks Differentially Recruited for Social and Cognitive Control Functions.

    Journal of neurophysiology·2026
    Same journal

    Comprehensive Analysis of Auditory Nerve Fiber Responses using Fiber-Specific Modeling.

    Journal of neurophysiology·2026
    See all related articles

    Cold-sensing nerve fibers in rats transmit temperature information to the brain. Second-order neurons faithfully relay this sensory input, indicating their activity depends on these afferent fibers.

    Area of Science:

    • Neuroscience
    • Sensory Physiology

    Background:

    • Cold sensation is mediated by specific afferent nerve fibers.
    • The trigeminal system processes somatosensory information, including temperature.
    • Understanding the neural pathways of cold perception is crucial.

    Purpose of the Study:

    • To investigate the responses of cold-receptive afferent fibers in the trigeminal ganglion.
    • To examine the activity of second-order neurons in the caudal trigeminal nucleus that receive input from these cold fibers.
    • To determine the source of continuous activity in these second-order neurons.

    Main Methods:

    • Extracellular recordings from trigeminal ganglion afferents and caudal trigeminal nucleus neurons in anesthetized rats.
    • Application of controlled thermal stimuli (steady and changing temperatures) to receptive fields.

    Related Experiment Videos

  • Assessment of static and dynamic neuronal responses.
  • Evaluation of neuronal activity following ganglionectomy.

    • Main Results:

    • Cold-receptive afferent fibers exhibited static and dynamic responses to thermal stimuli.
    • Second-order neurons in the caudal trigeminal nucleus mirrored the afferent fiber responses but with higher activity levels.
    • Ganglionectomy abolished the spontaneous activity of second-order neurons.

    Conclusions:

    • Second-order neurons in the caudal trigeminal nucleus accurately relay cold sensory information from trigeminal afferents.
    • The high level of activity in these second-order neurons is tonically driven by afferent input.
    • Intrinsic medullary circuits do not appear to generate the continuous activity observed in these neurons.