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Autism Spectrum Disorder

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.

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Related Experiment Video

Updated: Jun 26, 2025

Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders

Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders

Published on: May 12, 2015

Debugging neurodevelopment disorders.

Jennie Sotelo-Orozco¹, Diana H Taft²

¹Department of Public Health Sciences, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.

Cell Host & Microbe

|May 9, 2024

Summary

This summary is machine-generated.

The gut microbiome may play a role in neurodevelopmental disorders. This study provides evidence linking gut bacteria to these conditions in children, though causality requires further investigation.

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Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders

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Area of Science:

Microbiology
Neuroscience
Developmental Biology

Background:

The gut microbiome's influence on brain health is increasingly recognized.
The specific role of gut bacteria in neurodevelopmental disorders remains largely undefined.

Purpose of the Study:

To investigate the association between the gut microbiome and neurodevelopmental disorders in a large pediatric cohort.
To explore the potential causal or predictive role of gut bacteria in neurodevelopment.

Main Methods:

Prospective longitudinal study design.
Analysis of gut microbiome composition in thousands of children.
Correlation of microbial patterns with neurodevelopmental outcomes.

Main Results:

Evidence suggesting a link between the gut microbiome and neurodevelopmental disorders.
Identification of specific microbial signatures potentially associated with these conditions.

Conclusions:

The gut microbiome is implicated in neurodevelopmental disorders.
Further research is needed to establish causality and predictive value.