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Lifileucel: the first cellular therapy approved for solid tumours
Max Julve1, Mark P Lythgoe2, James Larkin1
1Department of Medical Oncology, The Royal Marsden NHS Foundation Trust, London, UK.
Abstract:
The US Food and Drug Administration (FDA) approval of lifileucel, for advanced melanoma, represents the first cellular therapy to reach the clinic for solid cancers. Here, we summarise this landmark approval, consider the associated regulatory pathway, and evaluate the challenges that remain to ensure effective implementation of this advanced 'living' therapy.
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