Related Experiment Video

Updated: Jun 26, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.0K

Exploring the optimal lower blood pressure boundary during endovascular thrombectomy in patients with large vessel

Yu-Ming Chang1, Chun-Min Wang1, Kang-Po Lee2

  • 1Department of Neurology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Journal of the Formosan Medical Association = Taiwan Yi Zhi
|May 9, 2024
PubMed

Insights

Maintaining systolic blood pressure (SBP) above 130-140 mmHg during endovascular therapy (EVT) may improve functional outcomes. Minimizing blood pressure fluctuations during EVT is also associated with better results.

Area of Science:

  • Neurology
  • Interventional Radiology
  • Cardiovascular Medicine

Background:

  • Current guidelines recommend maintaining blood pressure (BP) below 180/105 mmHg during endovascular therapy (EVT).
  • The optimal lower BP boundary during EVT is not well-established and is largely based on expert consensus.
  • This study investigates the relationship between specific lower BP targets and functional outcomes after EVT.

Purpose of the Study:

  • To determine the correlation between various lower boundary targets for systolic BP (SBP) and diastolic BP (DBP) during EVT and 3-month functional outcomes.
  • To explore the association between periprocedural BP variability and functional outcomes following EVT.

Main Methods:

  • A cohort study involving 201 patients with large artery occlusion undergoing EVT within 8 hours of stroke onset.
  • Mean BP values during EVT were recorded, and logistic regression models were used to assess the association between BP targets and outcomes.
  • Analysis also included the relationship between BP variability and functional outcomes.

Main Results:

  • An SBP higher than 130 or 140 mmHg was independently associated with improved functional outcomes at 3 months (aOR 2.34-2.80).
  • SBP exceeding 130 mmHg correlated with decreased 3-month mortality (aOR 0.24).
  • Higher periprocedural SBP variability was linked to poorer functional outcomes (aOR 0.42). No significant association was found for DBP targets.

Conclusions:

  • A systolic BP range above 130-140 mmHg may represent a safe lower boundary during EVT.
  • Minimizing BP fluctuations during EVT could be crucial for improving functional outcomes.
  • These findings suggest potential adjustments to BP management strategies during EVT.
Abstract

Keywords:
Acute ischemic strokeBlood pressure variabilityEndovascular thrombectomyPeriprocedural blood pressure

More Related Videos

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound13:48

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

Published on: April 21, 2023

1.5K
Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke09:00

Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke

Published on: February 10, 2023

1.2K

Related Concept Videos

Pre-Procedural Guidelines for Assessing Blood Pressure01:10

Pre-Procedural Guidelines for Assessing Blood Pressure

Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
562
Assessment of blood pressure in brachial artery(one-step method)01:15

Assessment of blood pressure in brachial artery(one-step method)

This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
585
Special considerations while measuring blood pressure01:28

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
721
Sites for measruring blood pressure01:21

Sites for measruring blood pressure

Blood pressure measurement is a fundamental clinical procedure, providing crucial data for assessing cardiovascular health. Among the various sites for this measurement, the brachial and popliteal arteries are predominantly utilized due to their accessibility and the reliability of their readings. This lesson delves into the anatomical significance, methodology, and considerations of measuring blood pressure at these locations.
The Brachial Artery: Primary Site for Blood Pressure Measurement
1.7K