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Updated: Jun 26, 2025

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
The effect of e-cigarettes on cognitive function: a scoping review.
Marissa L Novak1, Grace Y Wang2,3
1School of Psychology and Wellbeing, University of Southern Queensland, Ipswich, Australia.
Electronic cigarettes (e-cigarettes) appear to have minimal acute cognitive effects on current smokers. However, their long-term cognitive impacts, especially on adolescents and nicotine-naïve individuals, require further investigation.
Area of Science:
- Neuroscience
- Public Health
- Behavioral Science
Background:
- Nicotine's acute cognitive effects are well-researched, showing varied impacts.
- Electronic cigarettes (e-cigarettes) are increasingly used for smoking cessation, but their cognitive effects are less understood.
- Research is needed to clarify e-cigarette cognitive effects, with or without nicotine.
Purpose of the Study:
- To review empirical evidence on the cognitive effects of e-cigarettes.
- To synthesize findings on e-cigarette use in smokers and non-smokers.
- To identify gaps in knowledge regarding long-term cognitive impacts.
Main Methods:
- Systematic review following PRISMA-ScR guidelines.
- Searched SCOPUS, PubMed, and EBSCOhost from 2006 to June 2023.
- Included 7 experimental and 4 cross-sectional studies, checking reference lists.
Main Results:
- Most studies focused on acute effects in current cigarette smokers.
- E-cigarettes showed minimal to positive cognitive effects in smokers.
- Some studies reported cognitive impairments (memory, concentration, decision-making) in both smokers and never-smokers.
Conclusions:
- Acute cognitive effects of e-cigarettes on smokers seem minimal.
- Long-term cognitive effects and impacts on never-smokers remain unclear.
- Further research on long-term effects in nicotine-naïve individuals and adolescents is crucial.
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