A Cross-Sectional Study of Hematological Parameters in the Geriatric Population Using Peripheral Smear Examination

Bhavinee Pathak1, Sabiha Maimoon1

  • 1Pathology, NKP (Narendra Kumar Prasadrao) Salve Institute of Medical Sciences, Nagpur, IND.

Cureus
|May 10, 2024
PubMed

Insights

Hematological parameters in the elderly are often abnormal, correlating with common conditions like diabetes mellitus, hypertension, and cardiovascular disease. These findings can serve as risk indicators for geriatric health.

Area of Science:

  • Geriatric Medicine
  • Hematology
  • Public Health

Background:

  • Healthy aging presents challenges, with older adults experiencing higher disease prevalence, particularly diabetes mellitus, hypertension (HTN), and cardiovascular illnesses.
  • Complete blood count (CBC) and peripheral blood smear analysis are crucial for assessing overall health and detecting various diseases in the elderly.
  • Investigating hematological parameters in the geriatric population is vital for understanding age-related health conditions.

Purpose of the Study:

  • To investigate hematological parameters in the elderly population.
  • To correlate CBC findings with common chronic ailments in seniors.
  • To utilize advanced hematology analyzers and peripheral smear tests for comprehensive geriatric health assessment.

Main Methods:

  • A cross-sectional study involving 188 patients aged 60 and above.
  • Data collected over two years from an outpatient department at a tertiary care institute.
  • Routine complete blood count and differential count analyzed using the Siemens Advia 2120 analyzer, with statistical analysis performed.

Main Results:

  • Hypertension (HTN), diabetes mellitus, cardiovascular disease (CVD), and generalized weakness were the most common conditions observed.
  • Decreased hemoglobin (Hb) showed a positive correlation with generalized weakness.
  • Elevated total leukocyte count (TLC) was more prevalent in patients with CVD and HTN.
  • Increased red cell distribution width (RDW) percentage was noted in elderly individuals with diabetes mellitus and CVD.

Conclusions:

  • Significant deviations from normal hematological parameters were observed in the elderly population.
  • These abnormal hematological parameters are associated with various prevalent health issues in seniors.
  • Parametric associations identified can serve as valuable risk indicators for healthcare professionals to ensure geriatric health.
Abstract

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