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Biomedical blockchain with practical implementations and quantitative evaluations: a systematic review.

Roger Lacson1, Yufei Yu2,3, Tsung-Ting Kuo2,3

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Blockchain shows promise for healthcare data sharing, but practical implementation and evaluation metrics are needed for widespread adoption. Further research is required to fully understand its impact on the health sector.

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Area of Science:

  • Biomedical Informatics
  • Distributed Ledger Technology
  • Health Data Management

Background:

  • Blockchain offers decentralization, immutability, and traceability for healthcare data sharing.
  • Existing reviews lack comprehensive investigation into practical blockchain implementation and evaluation in biomedicine.

Purpose of the Study:

  • To systematically review and assess blockchain applications implemented in the biomedical domain.
  • To evaluate these applications using quantitative metrics.

Main Methods:

  • A systematic review adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework.
  • Searched 3 databases for biomedical blockchain papers published by August 2023.
  • Collected and summarized data on blockchain application, implementation, and evaluation metrics.

Main Results:

  • 11 articles were included, covering applications like COVID-19 data sharing, IoT data storage, clinical trials, and electronic health records (EHR).
  • Ethereum was the predominant platform, with most implementations using private networks.
  • Only one study reported deployment in a medical facility; storage and query speed metrics were reported in some studies.

Conclusions:

  • Blockchain is feasible for healthcare but not yet as prevalent as existing data management technologies.
  • Inconsistent metrics and limited study numbers hinder direct technological comparisons.
  • Addressing implementation and evaluation is crucial to demonstrate blockchain's practical benefits in healthcare.