Related Experiment Video
Updated: Jun 26, 2025

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
Pillararenes: a new frontier in antimicrobial therapy
Yanqing Jin1, Yisu Liu1, Jiang Zhu2
1Key Laboratory for Green Chemical Process of Ministry of Education, School of Chemical Engineering & Pharmacy, Wuhan Institute of Technology, 693 Xiongchu Avenue, Wuhan 430073, P. R. China. witty_lau@hotmail.com.
Abstract:
Pillararenes have gained great interest among researchers in many fields due to their symmetric structure and facile functionalization. In this review, we summarize recent progress for pillararenes as antimicrobial agents, ranging from cationic pillararenes and peptide-modified pillararenes to sugar-functionalized pillararenes. Moreover, their structure-activity relationships are presented, and their mechanisms of action are discussed. As a state-of-the-art technology, their opportunities and outlook are also outlined in this emerging field. Overall, their potent inhibitory activity and high biocompatibility give them potential for the development of novel antimicrobial agents.
More Related Videos
10:26P. aeruginosa Infected 3D Co-Culture of Bronchial Epithelial Cells and Macrophages at Air-Liquid Interface for Preclinical Evaluation of Anti-Infectives
Published on: June 15, 2020
12:03Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
Published on: April 18, 2019
Related Concept Videos
Surface Membrane Barriers
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Antimicrobial Proteins
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Combined Effects of Drugs: Synergism
Such synergistic combinations...