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Research related to validation of treatment modalities by large-scale clinical trials
Circulation
|December 1, 1979
Abstract:
The history of randomized, controlled, clinical trials is reviewed. Cooperative clinical trials are reviewed and summarized, and specific needs for future trials are identified. Improved policy on resource allocation decisions for clinical trials vs other forms of research is necessary, particularly as such trials begin to translate improved therapeutic knowledge into community level disease control.
Insights
This review examines the history and future needs of cooperative clinical trials. Enhanced policy for resource allocation is crucial for translating research into community disease control.
Area of Science:
- Clinical Research
- Public Health Policy
- Epidemiology
Background:
- The evolution of randomized, controlled, clinical trials (RCCTs) is a critical aspect of medical research.
- Cooperative clinical trials have played a significant role in advancing therapeutic knowledge and disease control strategies.