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Prompt-gamma track-length estimator with time tagging from proton tracking.

Jean M Létang1, Oreste Allegrini2, Étienne Testa2

  • 1INSA-Lyon, Universite Claude Bernard Lyon 1, CNRS UMR5220, Inserm U1294, Centre Léon Bérard, CREATIS, F-69373 Lyon, France.

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This study enhances Monte Carlo simulations for proton therapy detectors by adding prompt-gamma emission time tagging to the GATE vpgTLE module, improving accuracy for detector design.

Keywords:
Monte Carlo (MC) simulationsprompt gamma (PG)track length estimator (TLE)variance reduction techniques (VRT)

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Area of Science:

  • Medical Physics
  • Computational Physics

Background:

  • Proton therapy requires Monte Carlo (MC) simulations for detector design and optimization.
  • Variance reduction techniques are crucial for accelerating MC simulations.
  • Track-length estimators (TLEs) offer speed and accuracy in MC simulations of rare events.

Purpose of the Study:

  • To introduce an extension of the GATE vpgTLE module incorporating prompt-gamma emission time tagging.
  • To enhance the utility of MC simulations for detector design and optimization studies relying on time measurements.

Main Methods:

  • Extension of the Geant4 Application for Tomographic Emission (GATE) vpgTLE module.
  • Incorporation of prompt-gamma emission time tagging, synchronized with proton tracking.
  • Validation using a clinical radiotherapy plan.

Main Results:

  • The enhanced vpgTLE module with time tagging demonstrates accurate results for prompt-gamma detection.
  • Accuracy is maintained across most prompt-gamma lines, with minor discrepancies for long mean-life nuclei.

Conclusions:

  • The new vpgTLE tally with time tagging is a valuable tool for prompt-gamma detector design in proton therapy.
  • This enhancement improves the precision of time-dependent measurements in MC simulations for proton therapy applications.