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The Urinary Microbiome: Improving Diagnostics and Management of Urinary Tract Infections in Adult Females
Toby C Chai1, Alan J Wolfe2, Linda Brubaker3
1Department of Urology, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, 725 Albany Street, Suite 3B, Boston, MA 02118, USA.
Abstract:
This article discusses the urinary microbiome in relation to urinary tract infection (UTI) in women. It makes biologic sense that the microbiota of different niches (bladder, vagina, and gut) interact with each other in health, as well as during a UTI event; however, these relationships remain poorly understood. Future research should close knowledge gaps regarding the interactions between the urinary microbiota and the host, amongst the microbiota of adjacent niches, and between the microbes within the same microbiota. The new knowledge should result in improved UTI treatment in the age of antibiotic stewardship.
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